Chromosomal Region 11p14.1 is Associated with Pharmacokinetics and Pharmacodynamics of Bisoprolol.

Vanessa FontanaRichard Myles TurnerBen FrancisPeng YinBenno Pütz Timo P HiltunenSanni RuotsalainenKimmo K KontulaBertam Müller-MyhsokMunir Pirmohamed

Published in: Pharmacogenomics and personalized medicine (2022)

A novel locus on the chromosomal region 11p14.1 was associated with bisoprolol clearance in a real-world cohort of patients and was validated in independent cohort with a pharmacodynamic association.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
peritoneal dialysis
gene expression
patient reported outcomes
dna methylation
patient reported