Optimization of a Rabbit Dry Eye Model Induced by Topical Instillation of Benzalkonium Chloride.
Carlos Carpena-TorresJesús PintorMaría Jesús Pérez de LaraFernando Huete-ToralAlmudena CrookeCristina PastranaGonzalo CarracedoPublished in: Journal of ophthalmology (2020)
The topical instillation of 0.2% BAC for 5 consecutive days, twice daily, was a proper procedure to induce a rabbit dry eye model, reducing the number of days of instillation compared to the original model (14 days).