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A palladium-catalyzed cascade process for spirooxindole: an alternative way for the synthesis of spiro(indoline-3,2'-quinazolin)-2-ones.

Abhilash SharmaDhiraj DuttaPranjal Gogoi
Published in: Organic & biomolecular chemistry (2021)
A palladium-catalyzed cascade strategy has been developed for one-pot synthesis of functionalized spiro(indoline-3,2'-quinazolin)-2-one derivatives from readily available starting materials. The reaction proceeds via C-C and two C-N bond formations in a single reaction operation. This method offers an attractive pathway for the synthesis of a broad range of spiro(indoline-3,2'-quinazolin)-2-ones in good yields.
Keyphrases
  • simultaneous determination