Feasibility of Direct Vitrectomy-Sparing Subretinal Injection for Gene Delivery in Large Animals.

Zbynek StranakTaras ArdanYaroslav NemeshMaria TomsLyes ToualbiRichard HarbottleZdenka EllederovaLyubomyr LytvynchukGoran PetrovskiJan MotlikMariya MoosajeeIgor Kozak

Published in: Current eye research (2024)

This pilot study demonstrates that successful subretinal delivery of gene therapy vectors is achievable using a direct injection without prior vitrectomy surgery.

Keyphrases

gene therapy
diabetic retinopathy
minimally invasive
ultrasound guided
coronary artery bypass
surgical site infection
atrial fibrillation