Improvising and developing state of the art techniques for breast cancer detection have always been an area of great interest in the field of imaging. Adding intravenous contrast to any imaging study, is well-known to increase the sensitivity and specificity of detection of a pathological process, especially in the setting of neoplasia secondary to tumor neoangiogenesis. Contrast enhanced MRI is known to be highly sensitive breast cancer screening tool till date, however, has been limited by long scan times, claustrophobia experienced by some women and high false positive findings. Despite continued advances in digital mammography technique, significant limitations have always been experienced in detection of small cancers especially in the setting of dense breast parenchyma. Implementing dual energy subtraction technique to digital mammography, made contrast enhanced mammography a viable technique to improve cancer detection. We aim to discuss the status of contrast enhanced mammography in this brief communication, emphasizing technical background, image acquisition, clinical applications, and future directions.
Keyphrases
- contrast enhanced
- computed tomography
- diffusion weighted
- dual energy
- magnetic resonance imaging
- magnetic resonance
- diffusion weighted imaging
- high resolution
- loop mediated isothermal amplification
- label free
- current status
- real time pcr
- papillary thyroid
- pregnant women
- squamous cell carcinoma
- quality improvement
- low dose
- skeletal muscle
- single molecule
- fluorescence imaging
- quantum dots
- tandem mass spectrometry
- structural basis
- pregnancy outcomes