The Impact of Race-Ethnicity and Diagnosis of Alzheimer's Disease and Related Dementias on Mammography Use.
Aokun ChenYongqiu LiJennifer N WoodardJessica Y IslamShuang YangThomas J GeorgeElizabeth A ShenkmanJiang BianYi GuoPublished in: Cancers (2022)
Breast cancer screening (BCS) with mammography is a crucial method for improving cancer survival. In this study, we examined the association of Alzheimer's disease (AD) and AD-related dementias (ADRD) diagnosis and race-ethnicity with mammography use in BCS-eligible women. In the real-world data from the OneFlorida+ Clinical Research Network, we extracted a cohort of 21,715 BCS-eligible women with ADRD and a matching comparison cohort of 65,145 BCS-eligible women without ADRD. In multivariable regression analysis, BCS-eligible women with ADRD were more likely to undergo a mammography than the BCS-eligible women without ADRD (odds ratio [OR] = 1.19, 95% confidence interval [CI] = 1.13-1.26). Stratified by race-ethnicity, BCS-eligible Hispanic women with ADRD were more likely to undergo a mammography (OR = 1.56, 95% CI = 1.39-1.75), whereas BCS-eligible non-Hispanic black (OR = 0.72, 95% CI = 0.62-0.83) and non-Hispanic other (OR = 0.65, 95% CI = 0.45-0.93) women with ADRD were less likely to undergo a mammography. This study was the first to report the impact of ADRD diagnosis and race-ethnicity on mammography use in BCS-eligible women using real-world data. Our results suggest ADRD patients might be undergoing BCS without detailed guidelines to maximize benefits and avoid harms.
Keyphrases
- contrast enhanced
- polycystic ovary syndrome
- image quality
- pregnancy outcomes
- magnetic resonance imaging
- end stage renal disease
- magnetic resonance
- breast cancer risk
- electronic health record
- newly diagnosed
- chronic kidney disease
- big data
- cognitive decline
- cervical cancer screening
- machine learning
- squamous cell carcinoma
- adipose tissue
- african american
- deep learning
- prognostic factors
- skeletal muscle
- artificial intelligence
- drug induced