Impaired Antibody Response Is Associated with Histone-Release, Organ Dysfunction and Mortality in Critically Ill COVID-19 Patients.
Rickard LagedalOskar ErikssonAnna SörmanJoram B HuckriedeBjarne KristensenStephanie FranzénAnders O LarssonAnders BergqvistAlving KjellAnders ForslundBarbro PerssonKristina N EkdahlPablo García de FrutosBo NilssonGerry A F NicolaesMiklos LipcseyMichael HultströmRobert FrithiofPublished in: Journal of clinical medicine (2022)
In patients with severe COVID-19 requiring intensive care, a poor antibody response is associated with organ failure, systemic histone release and increased 30-day mortality.