Interaction of Sirtuin 1 (SIRT1) candidate longevity gene and particulate matter (PM2.5) on all-cause mortality: a longitudinal cohort study in China.
Yao YaoLinxin LiuGuang GuoYi ZengJohn S JiPublished in: Environmental health : a global access science source (2021)
We found a gene-environment interaction of SIRT1 and air pollution on mortality, future experimental studies are warranted to depict the mechanism observed in this study.
Keyphrases
- particulate matter
- air pollution
- copy number
- genome wide
- lung function
- oxidative stress
- ischemia reperfusion injury
- genome wide identification
- cardiovascular events
- current status
- dna methylation
- type diabetes
- risk assessment
- cardiovascular disease
- genome wide analysis
- heavy metals
- chronic obstructive pulmonary disease