Stromal cartilage oligomeric matrix protein as a tumorigenic driver in ovarian cancer via Notch3 signaling and epithelial-to-mesenchymal transition.

Gilar Gorji-BahriB Madhu KrishnaCatharina HagerlingAkira OrimoKarin JirströmKonstantinos S PapadakosAnna M Blom

Published in: Journal of translational medicine (2024)

This study suggests that COMP secretion by CAFs drives ovarian cancer progression through the induction of the Notch pathway and epithelial-to-mesenchymal transition.

Keyphrases

bone marrow
cell proliferation
amino acid
small molecule