Diagnostic accuracy of antigen detection in urine and molecular assays testing in different clinical samples for the diagnosis of progressive disseminated histoplasmosis in patients living with HIV/AIDS: A prospective multicenter study in Mexico.
Areli Martínez-GamboaMaría Dolores Niembro-OrtegaPedro Torres-GonzálezJaneth Santiago-CruzNancy Guadalupe Velázquez-ZavalaAndrea Rangel-CorderoBrenda E Crabtree-RamírezArmando Gamboa-DomínguezEdgardo Reyes-GutiérrezGustavo Reyes-TeránVíctor Hugo Lozano-FernandezAhumada-Topete Víctor HugoPedro Martínez-AyalaMarisol Manríquez-ReyesJuan Pablo Ramírez-HinojosaPatricia Rodríguez-ZuluetaChristian Hernández-LeónJesús Arturo Ruiz QuiñonesNorma Eréndira Rivera-MartínezAlberto Chaparro-SánchezJaime Federico Andrade-VillanuevaLuz Alicia González-HernándezSofia Cruz-MartínezOscar Flores-BarrientosJesús Enrique Gaytán-MartínezMartín Magaña-AquinoAxel Cervantes-SánchezAntonio Olivas-MartínezJavier Araujo-MeléndezMaría Del Rocío Reyes-MontesEsperanza Duarte-EscalanteMaría Guadalupe Frías De LeónJosé Antonio RamírezMaria Lucia TaylorAlfredo Ponce de León-GarduñoJosé Sifuentes-OsornioPublished in: PLoS neglected tropical diseases (2021)
The cHGEI IMMY and MVHUALFA tests showed excellent performance for the diagnosis of PDH in PLWHIV. The integration of these tests in clinical laboratories will certainly impact on early diagnosis and treatment.