Ebi3 knockout aggravates experimental periodontitis via Th17 polarization.

Hisashi GotoTakeshi KikuchiYuhei TakayanagiYosuke KamiyaYuki SuzukiShotaro KawamuraNoritaka SawadaJun-Ichiro HayashiAkio Mitani

Published in: Journal of clinical periodontology (2023)

Together, these findings suggest that Th17 cells exacerbate experimental periodontitis in mice lacking Ebi3 and that IL-35 may play a critical role in inhibiting periodontal tissue destruction.

Keyphrases

induced apoptosis
cell cycle arrest
signaling pathway
high fat diet induced
cell death
type diabetes
pi k akt