TP53 Alterations Are Associated With Poor Survival in Patients With Primary Mediastinal Nonseminoma Germ Cell Tumors.

Jack V W BaconPatrizia GiannatempoGiovanna CataldoLadan FazliNeetu SaxenaGuliz OzgunMaryam SoleimaniKim ChiCraig NicholsAndrea NecchiAlexander W WyattChristian K KollmannsbergerLucia Nappi

Published in: The oncologist (2022)

TP53 alterations are common in PMNSGCT and are associated with reduced overall survival, potentially underlying the poor sensitivity to chemotherapy observed in these patients.

Keyphrases

germ cell
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
lymph node
peritoneal dialysis
prognostic factors
squamous cell carcinoma
locally advanced
patient reported outcomes
ultrasound guided