Absolute CD4+ T cell count overstate immune recovery assessed by CD4+/CD8+ ratio in HIV-infected patients on treatment.
Yusnelkis Milanés-GuisadoAlicia Gutiérrez-ValenciaMaría Trujillo-RodríguezNuria EspinosaPompeyo VicianaLuis Fernando López-CortésPublished in: PloS one (2018)
The increases in aCD4 poorly correlate with those of CD4% and CD4/CD8. IR rates based on aCD4 significantly overstate those obtained by CD4% and CD4/CD8. CD4% and CD4/CD8 are more stable markers than aCD4 and should be taken into account to monitor the IR after treatment initiation.