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Single-cell transcriptome analysis revealed a suppressive tumor immune microenvironment in EGFR mutant lung adenocarcinoma.

Lei YangYun-Ting HeSong DongXue-Wu WeiZhi-Hong ChenBo ZhangWei-Dong ChenXiao-Rong YangFen WangXue-Meng ShangWen-Zhao ZhongYi-Long WuQing Zhou
Published in: Journal for immunotherapy of cancer (2022)
TRM might be a key factor responsible for the suppressive TME of EGFR-mutant LUAD.
Keyphrases
  • single cell
  • small cell lung cancer
  • epidermal growth factor receptor
  • tyrosine kinase
  • rna seq
  • wild type
  • stem cells
  • high throughput