Characterization of RHD locus polymorphism in D negative and D variant donors from Northwestern Argentina.

Carolina Trucco BoggioneNúria NoguésCecilia González-SantestebanNicolás MufarregeMelina Luján BrajovichStella Maris MattaloniMónica LeriClaudia BiondiEduardo Muñiz-DiazLilian CastilhoCarlos Cotorruelo

Published in: Transfusion (2019)

A RHD genotyping strategy for patients and donors from Northwestern Argentina must consider the detection of the frequently found RHD*01N.75, RHD*DEL43, and RHD*weak D type 93 variants. Taking into account that RHD*DEL43 has scarcely been found in North Americans and Europeans whereas RHD*01N.75 and RHD*weak D type 93 have never been described in populations other than Argentineans, these RHD variants could be attributed to Native Amerindian genetic influence.

Keyphrases

prognostic factors
copy number
genome wide
end stage renal disease
kidney transplantation
peritoneal dialysis
newly diagnosed
tertiary care
quantum dots