Nuclear translocation of YAP drives BMI1-associated hepatocarcinogenesis in hepatitis B virus infection.

Xufeng LuoRui ZhangStefan SchefczykYaojie LiangShu S LinShi LiuHideo A BabaChristian M Lange Heiner Wedemeyer Mengji Lu Ruth Broering

Published in: Liver international : official journal of the International Association for the Study of the Liver (2023)

HBV-associated proliferative HCC might be related to the HBsAg-YAP-BMI1 axis and offer a potential target for the development of new therapeutic approaches.

Keyphrases

hepatitis b virus
body mass index
weight gain
liver failure
physical activity
human health
drug induced
weight loss