Relationship between MRGPRX2 and pethidine hydrochloride- or fentanyl citrate-induced LAD2 cell degranulation.

Rui LiuJue WangTingting ZhaoJiao CaoDelu ChePengyu MaYongjing ZhangTao ZhangNan Wang

Published in: The Journal of pharmacy and pharmacology (2018)

PH but not FC activated mast cells, leading to degranulation mediated via MRGPRX2 receptors, which could be greatly significant in future clinical applications of opioid receptor drugs.

Keyphrases

chronic pain
single cell
high glucose
pain management
drug induced
diabetic rats
cell therapy
current status
mesenchymal stem cells
binding protein