STochastic Optical Reconstruction Microscopy (STORM) reveals the nanoscale organization of pathological aggregates in human brain.

Philippe CodronF LetournelS MartyL RenaudA BodinMathilde DuchesneC VernyG LenaersC DuyckaertsJ-P JulienJ CassereauA Chevrollier

Published in: Neuropathology and applied neurobiology (2020)

STORM imaging of human brain samples opens further gates to a more comprehensive understanding of common neurological disorders. The convenience of this technique should open a straightforward extension of its application for super-resolution imaging of the human brain, with promising avenues to current challenges in neuroscience.

Keyphrases

high resolution
high speed
atomic force microscopy
mass spectrometry
single molecule
fluorescence imaging