Continued versus interrupted direct oral anticoagulation for cardiac electronic device implantation: A systematic review.

Pablo A MendozaSukrit NarulaWilliam F McintyreRichard P WhitlockDavid H BirnieJeff S HealeyEmilie P Belley-Côté

Published in: Pacing and clinical electrophysiology : PACE (2020)

Continuing DOACs for device implantation results in little to no difference in the incidence of clinically significant pocket hematoma or thromboembolism. Given the ease of stopping and restarting DOACs, interrupting DOACs may be the preferred strategy for most patients. However, whenever continuous therapeutic anticoagulation is desired, DOAC continuation should be preferred over bridging with parenteral anticoagulation.

Keyphrases

direct oral anticoagulants
venous thromboembolism
atrial fibrillation
end stage renal disease
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors
heart failure
risk factors