Genetically engineering glycolysis in T cells increases their antitumor function.
Raphaëlle Toledano ZurOrna AtarTilda BarliyaShiran HoogiIfat AbramovichEyal GottliebNoga Ron-HarelCyrille J CohenPublished in: Journal for immunotherapy of cancer (2024)
In summary, these findings support the implementation of T-cell metabolic engineering to enhance the efficacy of cellular immunotherapies for cancer.