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Complementary Role of P2 and Adenosine Receptors in ATP Induced-Anti-Apoptotic Effects Against Hypoxic Injury of HUVECs.

Catherine FeliuHélène PeyretGael PoitevinYoann CazaubonFloriane OszustPhilippe NguyenHervé MillartZoubir Djerada
Published in: International journal of molecular sciences (2019)
These results suggest a complementary role of P2 and adenosine receptors in ATP-induced protective effects against hypoxia injury of endothelial. This could be considered therapeutic targets to limit the development of ischemic injury of organs such as heart, brain, and kidney.
Keyphrases
  • high glucose
  • endothelial cells
  • diabetic rats
  • cell death
  • heart failure
  • drug induced
  • protein kinase
  • oxidative stress
  • cerebral ischemia