Serum neurofilament light chain: No clear relation to cognition and neuropsychiatric symptoms in stable MS.
Orhan AktasAlina RennerAndré HussMelanie FilserSharon BaetgeNathalie StuteMarcia GasisKlaudia LepkaNorbert GoebelsMakbule SenelJonas GrafChristian EnzingerDaniela PinterGerald AntochBernd TurowskiHans-Peter HartungPhilipp AlbrechtMarkus OttoHayrettin TumaniIris-Katharina PennerPublished in: Neurology(R) neuroimmunology & neuroinflammation (2020)
In patients with stable MS at less advanced disease stages, sNfL did not convincingly relate to cognitive performance, fatigue, depression, or anxiety and thus may not serve as a surrogate biomarker for neuropsychological status in such populations.