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Use of immune checkpoint inhibitors in patients with solid tumors and pre-existing autoimmune or inflammatory disease: real-world data.

Virginia CalvoMarta Andrés FernándezAna Collazo-LorduyFernando F FrancoBeatriz NúñezMariano Provencio
Published in: Lung cancer management (2021)
In our series, AID flare ups or irAEs in patients with pre-existing AID who receive immunotherapy are not very common and can often be controlled without interrupting treatment. Prospective studies are needed to establish the incidence of irAEs in patients with pre-existing autoimmune conditions, evaluate risk-benefit and elaborate management clinical guidelines in this population.
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