Ancestry specific distribution of LPA Kringle IV-Type-2 genetic variants highlight associations to apo(a) copy number, glucose, and hypertension.
Yihao LiFlorian KronenbergStefan CoassinBadri VardarajanGissette Reyes-SofferPublished in: medRxiv : the preprint server for health sciences (2024)
KIV-2 variants found in three ancestry groups, including data on Caribbean Hispanics, show strong positive associations to hypertension and negative associations to glucose levels. Further characterization of these variants and identifying links to disease can help precision medicine efforts to understand disease mechanisms in all populations.