Late-onset epilepsy and 25-year cognitive change: The Atherosclerosis Risk in Communities (ARIC) study.

Emily L Johnson Gregory L KraussKeenan A WalkerJason BrandtAnna Kucharska-NewtonThomas H MosleySevil YasarRebecca F Gottesman

Published in: Epilepsia (2020)

Global cognition, verbal memory, executive function, and word fluency declined faster over time in persons developing LOE than without LOE. Declines in cognition preceding LOE suggest these are linked; it will be important to investigate causes for midlife cognitive declines associated with LOE.

Keyphrases

late onset
early onset
working memory
mild cognitive impairment
white matter
cardiovascular disease
multiple sclerosis