Rapid changes in neuroendocrine regulation may contribute to reversal of type 2 diabetes after gastric bypass surgery.
Petros KatsogiannosPrasad G KambleUrban WiklundMagnus SundbomDaniel EspesUlf HammarF Anders KarlssonMaria J PereiraJan W ErikssonPublished in: Endocrine (2020)
There were rapid changes within 4 weeks after RYGB: signs of enhanced parasympathetic nerve activity, reduced morning cortisol, and enhanced incretin and glucagon responses to glucose. The findings suggest that neurohormonal mechanisms can contribute to the rapid improvement of insulin resistance and glycemia following RYGB in type 2 diabetes.
Keyphrases
- type diabetes
- roux en y gastric bypass
- gastric bypass
- insulin resistance
- weight loss
- loop mediated isothermal amplification
- glycemic control
- obese patients
- cardiovascular disease
- minimally invasive
- coronary artery bypass
- metabolic syndrome
- heart rate variability
- blood glucose
- skeletal muscle
- bariatric surgery
- acute coronary syndrome
- coronary artery disease
- high fat diet induced