Malformation of cortical development with abnormal cortex: early ultrasound diagnosis between 14 and 24 weeks of gestation.

Early diagnosis of malformations involving cortical development is possible with ultrasound, these patients probably represent the most severe cases and all had associated malformations. Callosal anomalies, the presence of an abnormal cortical layer and abnormal overdeveloped sulci appear to be early signs of malformations of cortical development. Familiarity with fetal brain anatomy and its early sonographic landmarks allowed early diagnosis of severe malformations of cortical development. This article is protected by copyright. All rights reserved.