Cognitive decline in older adults with epilepsy: The Cardiovascular Health Study.

Hyunmi ChoiEvan L ThackerWilliam T LongstrethMitchell S V ElkindAmelia K Boehme

Published in: Epilepsia (2020)

Faster decline in global cognitive ability seen in this study validates concerns of patients. ApoE4 allele status was an effect modifier of the relationship between cognitive decline and prevalent epilepsy. Further research is warranted to explore biological mechanisms and possible interventions to mitigate cognitive decline.

Keyphrases

cognitive decline
mild cognitive impairment
physical activity
end stage renal disease
chronic kidney disease
newly diagnosed
prognostic factors
adipose tissue
metabolic syndrome