Mmp13 and Adamts5 are critical downstream target genes involved in the TGFβ signaling pathway during the development of OA.
Keyphrases
- transforming growth factor
- epithelial mesenchymal transition
- signaling pathway
- knee osteoarthritis
- multiple sclerosis
- pi k akt
- rheumatoid arthritis
- copy number
- high fat diet induced
- genome wide
- induced apoptosis
- genome wide identification
- type diabetes
- extracellular matrix
- metabolic syndrome
- oxidative stress
- cell proliferation
- dna methylation
- transcription factor
- skeletal muscle
- genome wide analysis