Added value of histogram analysis of intravoxel incoherent motion and diffusion kurtosis imaging for the evaluation of complete response to neoadjuvant therapy in locally advanced rectal cancer.
Lan ZhangZiwei JinFan YangYiwan GuoYuan LiuManman ChenSi XuZhenyu LinPeng SunMing YangPeng ZhangKaixiong TaoTao ZhangXin LiChuangsheng ZhengPublished in: European radiology (2024)
Question The current conventional imaging evaluation system lacks adequacy for assessing CR to NAT in LARC. Findings Significantly improved diagnostic performance was observed with the histogram analysis of IVIM and DKI in conjunction with conventional MRI. Clinical relevance IVIM and DKI provide significant value in evaluating CR to NAT in LARC, which bears significant implications for reducing surgical complications and facilitating organ preservation.
Keyphrases
- diffusion weighted imaging
- rectal cancer
- locally advanced
- contrast enhanced
- diffusion weighted
- magnetic resonance imaging
- neoadjuvant chemotherapy
- high resolution
- squamous cell carcinoma
- phase ii study
- radiation therapy
- computed tomography
- magnetic resonance
- lymph node
- bone marrow
- stem cells
- mesenchymal stem cells
- clinical evaluation
- study protocol