Conditioned pain modulation and offset analgesia: Influence of sex, sex hormone levels and menstrual cycle on the magnitude and retest reliability in healthy participants.
Jan VollertNils TrewarthaDeborah KemkowskiAlexander Felix CremerPeter K ZahnDaniel SegelckeEsther Miriam Pogatzki-ZahnPublished in: European journal of pain (London, England) (2022)
This study investigated CPM and offset analgesia in parallel, across sexes and during two menstrual cycles while assessing the impact of sex hormones. Reliability seems to depend on experimental parameters rather than participant characteristics, while the magnitude of effect could be weakly linked to sex hormones and sex.