Separating the effects of early and later life adiposity on colorectal cancer risk: a Mendelian randomization study.
Nikos PapadimitriouCaroline J BullMazda JenabDavid J HughesJoshua A BellEleanor SandersonNicholas J TimpsonGeorge Davey SmithDemetrius AlbanesPeter T CampbellSébastien KüryLoic Le MarchandCornelia M UlrichKala VisvanathanJane C FigueiredoPolly A NewcombRish K PaiUlrike PetersKostas K TsilidisJolanda M A BoerEmma E VincentDaniela MariosaMarc J GunterTom G RichardsonNeil MurphyPublished in: BMC medicine (2023)
Our findings suggest that the positive association between early life body size and colorectal cancer risk is likely due to large body size retainment into adulthood.