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Comparison of Anterior Segment Abnormalities in Individuals With FOXC1 and PITX2 Variants.

Mallika Prem-SenthilLachlan S W KnightDeepa TaranathDavid A MackeyJonathan B RuddleMark Y ChiangOwen M SiggsEmmanuelle SouzeauJamie E Craig
Published in: Cornea (2022)
Corneal abnormalities were more common in individuals with FOXC1 than in those with PITX2 variants and were often associated with early onset glaucoma. These findings highlight that patients with FOXC1 variations require close follow-up and monitoring throughout infancy and into adulthood.
Keyphrases
  • early onset
  • late onset
  • copy number
  • depressive symptoms
  • cataract surgery
  • weight gain
  • wound healing
  • body mass index
  • early life
  • genome wide
  • gene expression
  • physical activity
  • dna methylation
  • weight loss