Brief Report: Blood and Genital Fluid Viral Load Trajectories Among Treated and Untreated Persons With Acute HIV Infection in Malawi.

Jane S ChenAudrey E PettiforJulie A E NelsonSam PhiriDana K PasqualeWiza KumwendaGift KamangaMackenzie L CottrellCraig SykesAngela D M KashubaGerald TeghaRobert KrysiakIsaac ThengoloseMyron S CohenIrving F HoffmanWilliam C MillerSarah E Rutstein

Published in: Journal of acquired immune deficiency syndromes (1999) (2022)

Although highly correlated, VLs in blood and genital fluids occupy discrete biological compartments with distinct virologic dynamics. Our results corroborate the dramatic reduction in both compartments after ART initiation. Increasing AHI screening and rapidly initiating treatment is key to interrupting transmission.

Keyphrases

antiretroviral therapy
hiv infected
liver failure
depressive symptoms
respiratory failure
drug induced
intensive care unit
aortic dissection