Assessment of Severity of Long QT Syndrome Phenotype and Risk of Fetal Death.
Lisa AlbertiniJordan E EzekianMelanie CareCandice SilversidesMathew SermerMichael H GollobDanna A SpearsPublished in: Journal of the American Heart Association (2023)
Women with long QT syndrome with more severe phenotypes have a higher incidence of fetal death. Maternal QTc is longer in pregnancies that result in fetal loss, and the birth weight of babies born to patients taking β-blockers with a QTc >500 ms is lower, suggesting that patients with more marked phenotype may experience worse fetal outcomes.
Keyphrases
- birth weight
- gestational age
- preterm birth
- end stage renal disease
- weight gain
- newly diagnosed
- chronic kidney disease
- ejection fraction
- mass spectrometry
- case report
- prognostic factors
- risk factors
- metabolic syndrome
- ms ms
- early onset
- type diabetes
- pregnant women
- body mass index
- low birth weight
- skeletal muscle
- preterm infants