Independent and incremental value of ventilation/perfusion PET/CT and CT pulmonary angiography for pulmonary embolism diagnosis: results of the PECAN pilot study.
Pierre-Yves Le RouxAmir IravaniJason CallahanKate BurburyPeter EuDaniel P SteinfortEddie LauBeverly WoonPierre-Yves SalaunRodney J HicksMichael S HofmanPublished in: European journal of nuclear medicine and molecular imaging (2019)
In this pilot study, we demonstrated the feasibility and potential utility of V/Q PET/CT for the management of patients with suspected PE. V/Q PET/CT may be of particular relevance in patients with equivocal findings or isolated subsegmental findings on CTPA, adding further discriminatory information to allow important decision-making regarding the use or withholding of anticoagulation. Given the other advantages of V/Q PET/CT (reduced acquisition time, low radiation dose), and with the increasing availability of 68Ga generators, PET/CT is a potential replacement for V/Q SPECT/CT imaging.
Keyphrases
- pet ct
- pulmonary embolism
- positron emission tomography
- computed tomography
- contrast enhanced
- decision making
- image quality
- inferior vena cava
- pulmonary hypertension
- atrial fibrillation
- dual energy
- intensive care unit
- magnetic resonance
- human health
- risk assessment
- mass spectrometry
- social media
- health information
- photodynamic therapy