Genome-wide association study of nocturnal blood pressure dipping in hypertensive patients.
Jenni M RimpeläIlkka H PörstiAntti JulaTerho LehtimäkiTeemu J NiiranenLasse OikarinenKimmo PorthanAntti TikkakoskiJuha VirolainenKimmo K KontulaTimo P HiltunenPublished in: BMC medical genetics (2018)
rs4905794 near BCL11B showed evidence for association with nocturnal BP dipping. It also associated with left ventricular mass in GENRES. Combined with earlier data, our results provide support to the idea that BCL11B could play a role in cardiovascular pathophysiology.
Keyphrases
- blood pressure
- hypertensive patients
- genome wide association study
- left ventricular
- heart rate
- electronic health record
- heart failure
- hypertrophic cardiomyopathy
- acute myocardial infarction
- big data
- cardiac resynchronization therapy
- obstructive sleep apnea
- left atrial
- mitral valve
- blood glucose
- type diabetes
- sleep apnea
- machine learning
- percutaneous coronary intervention
- depressive symptoms
- aortic valve
- catheter ablation