HIF-1α controls palatal wound healing by regulating macrophage motility via S1P/S1P1 signaling axis.
Islamy Rahma HutamiTakashi IzawaTsendsuren Khurel-OchirTakuma SakamakiAkihiko IwasaShuhei TomitaEiji TanakaPublished in: Oral diseases (2021)
HIF-1α deficiency aggravates M1 and M2 macrophage infiltration and controls macrophage motility via S1P/S1P1 signaling. These results suggest that HIF-1α signaling may contribute to the regulation of palatal wound healing.