UPLC-MS based serum metabolomics for early diagnosis of refractory tumor-induced osteomalacia: a case-control study.

Xiang LiYiyi GongQi ZhangXiaolin NiQianqian PangYue ChiRuizhi JiajueLijia CuiXu JiangOu WangXiaoping XingYan JiangMei LiWeibo Xia

Published in: The Journal of clinical endocrinology and metabolism (2023)

We investigate the global metabolomes of refractory TIO and identify potential prognostic biomarkers preliminarily. A high sensitivity and specificity panel were identified as promising discriminating predictor, which need to be verified in more patients. This work may demonstrate novel insights into TIO prognosis and pathogenesis.

Keyphrases

mass spectrometry
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
multiple sclerosis
prognostic factors
oxidative stress
risk assessment
patient reported outcomes
simultaneous determination
climate change
drug induced