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Comparison of Three Different Aqueous Microenvironments for Enhancing Oral Bioavailability of Sildenafil: Solid Self-Nanoemulsifying Drug Delivery System, Amorphous Microspheres and Crystalline Microspheres.

Jung Suk KimFakhar Ud DinSang Min LeeDong Shik KimMi Ran WooSeunghyun CheonSang Hun JiJong Oh KimYu Seok YounKyung Taek OhSoo-Jeong LimSung Giu JinHan-Gon Choi
Published in: International journal of nanomedicine (2021)
Therefore, solid SNEDDS could be recommended as an oral dosage form for enhancing the oral bioavailability of sildenafil.
Keyphrases
  • pulmonary hypertension
  • pulmonary arterial hypertension
  • ionic liquid
  • simultaneous determination
  • solid state