Clinico-pathological discrepancies in the diagnosis of causes of death in adults in Mozambique: A retrospective observational study.
Jaume OrdiPaola CastilloAlberto L Garcia-BasteiroCinta MoraledaFabiola FernandesLlorenç QuintóJuan Carlos HurtadoEmili LetangLucilia LovaneDercio JordaoMireia NavarroRosa BeneTacilta NhampossaMamudo R IsmailCesaltina LorenzoniAssucena GuisseveNatalia RakislovaRosauro VaroLorena MarimonAriadna SanzAnelsio CossaInacio MandomandoMaria MaixenchsKhátia MunguambeJordi VilaEusebio MacetePedro L AlonsoQuique BassatMiguel J MartínezCarla CarrilhoClara MenéndezPublished in: PloS one (2019)
Major clinico-pathological discrepancies are still frequent in resource constrained settings. Increasing the level of suspicion for infectious diseases and expanding the availability of diagnostic tests could significantly improve the recognition of common life-threatening infections, and thereby reduce the mortality associated with these diseases. The high frequency of clinico-pathological discrepancies questions the validity of mortality reports based on clinical data or verbal autopsy.