Retinal oximetry and fractal analysis of capillary maps in sickle cell disease patients and matched healthy volunteers.
Willem A J BirkhoffL van ManenJ DijkstraM L De KamJ C van MeursA F CohenPublished in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (2019)
Our study demonstrated the feasibility of multispectral imaging to measure retinal changes in oxygenation in both SCD patients and matched volunteers. The results suggest that in SCD patients before any structural microvascular changes in the central retina are present, functional abnormalities can be observed with abnormal oximetry measurements.