Regional ventilation distribution before and after laparoscopic lung parenchymal resection.
Zhibin XiaoLin YangMeng DaiWenjun LuFeng LiuInéz FrerichsChangjun GaoXude SunZhanqi ZhaoPublished in: Physiological measurement (2024)

The aim of the present study was to evaluate the influence of one-sided pulmonary nodule and tumour on ventilation distribution pre- and post- partial lung resection.
Methods:
A total of 40 consecutive patients scheduled for laparoscopic lung parenchymal resection were included. Ventilation distribution was measured with electrical impedance tomography (EIT) in supine and surgery lateral positions 72 hours before surgery (T1) and 48 hours after extubation (T2). Left lung to global ventilation ratio (Fl), the global inhomogeneity index (GI), standard deviation of regional ventilation delay (RVDSD) and pendelluft amplitude (Apendelluft) were calculated to assess the spatial and temporal ventilation distribution.
Results:
After surgery (T2), ventilation at the operated chest sides generally deteriorated compared to T1 as expected. For right-side resection, the differences were significant at both supine and left lateral positions (p<0.001). RVD was in general more heterogeneous. For left-side resection, RVDSD was worse at T2 compared to T1 at left lateral position (p=0.002). The other EIT-based parameters showed no significant differences between the two time points. No significant differences were observed between supine and lateral positions for the same time points respectively.
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