Role of Toothbrushes as Gene Expression Profiling Tool for Oral Cancer Screening in Tobacco and Alcohol Users.
Govindarajan SujathaVishnu Priya VeeraraghavanAhmed AlamoudiMaha A BahammamSarah Ahmed BahammamYaser Ali AlhazmiHazar S AlharbiKhalid J AlzahraniMohammad S Al-GhamdiFuad M AlzahraniSaranya VaradarajanA Thirumal RajShankaragouda PatilPublished in: International journal of environmental research and public health (2022)
A toothbrush is a good source of RNA, and gene expression analysis can be performed using the genetic material retrieved from toothbrushes, which can aid in the early diagnosis of oral squamous cell carcinoma among tobacco and alcohol users. Further studies with a larger sample size and different durations of toothbrush use should be conducted to explore the role of toothbrushes as a noninvasive tool for disease diagnosis.