Local islet remodelling associated with duct lesion-islet complex in adult human pancreas.

Yu-Wen TienHung-Jen ChienTsai-Chen ChiangMei-Hsin ChungChih-Yuan LeeShih-Jung PengChien-Chia ChenYa-Hsien ChouFu-Ting HsiaoYung-Ming JengShiue-Cheng Tang

Published in: Diabetologia (2021)

We identify local islet remodelling associated with PanIN-islet complex in the adult human pancreas. The tissue remodelling and the evidence of inflammation and stromal accumulation suggest that the PanIN-islet complex is derived from tissue repair after a local injury.

Keyphrases

endothelial cells
induced pluripotent stem cells
oxidative stress