Lkb1 aggravates diffuse large B-cell lymphoma by promoting the function of Treg cells and immune escape.

Xiuhua SuTao SunMeng LiYuan XiaMingying LiDongmei WangFei LuJingjing YeChun-Yan Ji

Published in: Journal of translational medicine (2022)

These findings confirmed that Lkb1-regulated Tregs are critical for immune escape in DLBCL, which emphasizes that Lkb1 is a potential target for the immunotherapy of DLBCL.

Keyphrases

diffuse large b cell lymphoma
epstein barr virus
induced apoptosis
cell cycle arrest
transcription factor
oxidative stress
cell proliferation