Elevated High-Sensitivity C-Reactive Protein Level Enhances the Impact of Lipoprotein(a) on Platelet Reactivity in PCI Patients Treated with Clopidogrel.
Kexin ZhangJiawen LiYulong LiKailun YanPei ZhuXiaofang TangDeshan YuanYuejin YangRunlin GaoJin-Qing YuanXueyan ZhaoPublished in: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis (2024)
The isolated elevation of Lp(a) level was not an independent indicator for platelet reactivity, yet the concomitant elevation of Lp(a) and hs-CRP levels was significantly associated with increased platelet reactivity. Whether intensified antiplatelet therapy or anti-inflammatory strategies could mitigate the risks in patients presenting combined Lp(a) and hs-CRP elevation requires future investigation.
Keyphrases
- antiplatelet therapy
- percutaneous coronary intervention
- acute coronary syndrome
- end stage renal disease
- anti inflammatory
- ejection fraction
- coronary artery disease
- st segment elevation myocardial infarction
- acute myocardial infarction
- newly diagnosed
- chronic kidney disease
- st elevation myocardial infarction
- prognostic factors
- coronary artery bypass grafting
- peritoneal dialysis
- human health