Validating the ratio of insulin like growth factor binding protein 4 to sex hormone binding globulin as a prognostic predictor of preterm birth in Viet Nam: a case-cohort study.

Jane E HirstJ Jay BonifaceDung Puhong LeAshoka D PolpitiyaAngela C FoxThi Thai Kim VuThuan Trong DangTracey C FleischerNhu Thi Hong BuiDurlin E HickokPaul E KearneyGuy ThwaitesStephen H KennedyEvelyne KestelynThanh Quang Le

Published in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2024)

We have validated a novel serum biomarker for PTB risk stratification in a very different setting to the original study. Further research is required to determine appropriate ratio thresholds based on the prevalence of risk factors and the availability of resources and preventative therapies.

Keyphrases

preterm birth
risk factors
binding protein
low birth weight
gestational age
preterm infants
transcription factor
dna binding
growth hormone