The prothrombotic state associated with obesity-induced hypertension is reduced by cocoa and its main flavanols.

G M Rabadán-ChávezE Reyes-MaldonadoL Quevedo-CoronaN Paniagua-CastroG Escalona-CardosoMaria Eugenia Jaramillo Flores

Published in: Food & function (2018)

Our results showed that cocoa and its main flavanols may improve endothelial dysfunction and exert their antihypertensive effects by decreasing the prothrombotic state in rats fed a hypercaloric diet. Moreover, improvement of obesity-related metabolic disorders may also contribute to their BP-lowering effect.

Keyphrases

weight loss
blood pressure
insulin resistance
metabolic syndrome
high fat diet induced
type diabetes
weight gain
high glucose
physical activity
diabetic rats
adipose tissue
drug induced
endothelial cells