Luminescent solar concentrators (LSCs) are a class of wave-guiding devices that can harvest solar light and concentrate it to targeted smaller areas. When coupled with photovoltaic devices (PVs), LSCs hold the potential to be integrated into various application setups, especially for building facade integration toward net-zero-energy buildings. Developing reliable LSC fabrication methods with easy scalability, high adaptability, and device controllability has been an important research topic. In this work, we report an ultrasonic nebulization-assisted spray deposition technique to fabricate quantum dot (QD)-based LSCs (QD-LSCs). This method allows for the production of high-performance QD-LSCs with different device dimensions and geometries. In addition, the quality of the QD thin-film coating layer is relatively independent of the concentration and volume of the coating QD ink solution, allowing for deliberate programming and performance optimization of the resulting QD-LSC devices. We anticipate that this ultrasonic spray coating method can be widely applied to the manufacturing of high-quality LSC devices that are integrable to various applications.